I also go for Hotel by Boichi
I vote Goku of Jyoji arimori,because of the meaning of life in it and because of the development of story.
I nominate Succeed from Osamu Akimoto with AtelierBe-dama. A one shot from the Jump one shot series last year. Well paced story of an old granny who lives in a space station around Earth and who retells her life.
I support the nomination for Blame!
I'd also like to support Akira for Best Science Fiction.
I support Eden it's an endless world for best science fiction
I nominate Blame!
I nominate Gantz!
I recently came up to date with the latest chapters and I liked the live action movies as well.
My all time favourite manga is Blame!...the world that is created, the intriguing characters(even if short-lived), not to mention the ironic premise of the AIs role in saving mankind is something that puts Blame! among my top manga...but the art....the art just kicks it up to nr.1...which is why Blame! easily takes the cake in Sci-fi
Some quality works we got here for candidates. My vote goes to Blame!. Out of personal preferance for the art, setting, and characters. The sheer scale of the journey and the world that's been explored just makes everything seems insignificant. Empires could crumble, nuclear holocausts could occur, and no one would bat an eyelid, or even hear a whisper of it. It's just such an incredible mission that the protagonist is tasked to complete, and he does it almost as any human would, a step at a time. (the dude's just a billion times more resillient). The world here is stark, unrelenting, and amoral. Almost as if it took my worst feelings of living in a real life megacity and turned it up to eleven, while making it a whole lot more badass.
I don't know Hotel. Akira is too old school. Gantz is more gore/action than sci-fi for me. I never get Blame (If I remember well, the story begin with absolutely no explanation, you just don't know what you read ... and I could never read more than the beginning).
Pluto is not my fav manga but it's still from Urasawa ... So, I vote for Pluto but I'm not a big fan of sci-fi in mangas