It could matter if the creature had evolved to cause diseases in those that eat it. I heard if humans eat each other they go crazy because it's not healthy to eat our own species brains & possibly tissue too. I believe it has to do with the DNA not mixing well.
as a biology major, this offends me. eating flesh won't cause dna mixture, also like someone said the cause of insanity is mostly like from eating brains due to the high risk of catching Prion.