Madara was ousted by the Uchiha, he challenged Hashirama for his own goals, not for the goals of his clan who already swore loyalty to Hashirama so get your facts straight first.
1) Hiruzen failed because his teacher Tobirama set him up for failure. Not to mention, at no point in time was there any kind of peace talk between Konoha and the Uchiha, they were simply destroyed.
2) Sasuke lost his clan, and his brother mind raped him not once, but twice. He was then cursed by Orochimaru, and essentially left to his own devices as a 13 year old by his teacher Kakashi. He was a child who has suffered more trauma than any Uchiha before him, and is thus a special case. The fact is he wasn't given the proper support he needed, just like Naruto wasn't.
You must be delirious if you think hatred isn't common in humans. Humans are blank canvases when they are born, and can be turned into anything given what they experience.
And again, please read the manga. Madara was given Izuna's eyes, he didn't kill him. Hashirama even notes this, that Madara went nuts after the loss of his brother. If he killed him himself, do you think he'd go nuts?
As for a better solution than Tobirama's? You have to be kidding, a child could answer that questing. You sit the Uchiha clan down, show them your concerns, and ask them to let you help them get better and stay stable. You set up a support system, so in case one of them does lose someone close to them, they aren't just left alone so they can become evil. You don't isolate them, you instead bring them closer to the village, not farther from it. Make them the personal body guards to the Hokage. Have the Yamanaka clan go into their minds to make sure they are healthy and loyal, or shit even brainwash them.