I nominate Revy in Black Lagoon, Kiwako in Biorg Trinity and Saki from Destro 246.
I was supposed to vote for Kana- she was awesome. But then I saw Amir from Otoyomegatari in the poll- Kana had super powers. Amir shoots arrows at gazelles. On a galloping horse.
The hardest choice, Motoko in the end, popularity got me this time ...
Nikaido. Motoko would be my second choice (Ylfa third).