What I love most about Noblesse is that it appeals to both genders, so that there can be more diversity in the fanbase. I also love the fact that Frankenstein's character is so uptight, it cracks me up! He reminds me a bit of myself sometimes. Or at least I'd like to think so.
Another thing I love is the art. You don't see full-color works anywhere. It adds so much life and personality to the characters. I also like the contrast between how very rigid the characters seem to be... up until they are flung into action and battle scenes. The juxtaposition is so captivating.
Seeing as I'm not up to date, there is more to come on my list.
Offtopic: I started reading Noblesse because of Charlie
I really thought I wasn't going to like it because I thought it was another dumb vampire thing.
I'm glad I read it, it's great! The humor is really well-placed, too. M21's reaction to the banana made me laugh so hard. "... is there some secret behind the banana??"