Naw Fuji and Hori are definitely not friends lol. Both of them are already highly eccentric in ways that don't mesh well with people, I doubt multiplying that together would lead to social interactions between them
Hori is already known to be on good terms with Ashihara from WorldTrigger (see that one MHA volume extra he drew, apparently based on some joke between the two) who is at the very least known to have great humor and a love for references. I don't see why Fujimoto, who is obviously also a reference loving film buff, wouldn't mesh with him as well.
Though I think Horikoshi also just likes to do references, shoutouts and collabs in general. And his series is very well-suited for cool designs getting used as cameos.
As for the new series, I'd be glad if it was actually not a new comedy-/gag-series or even just light-hearted one for once. It seems like WSJ gets a ton of those recently (UU, Mashle, MYF, Mitama...).