other than kakashi who has the same eye power nobody is able to beat obito, sasuke won't be able to hit him with any of his techniques including amaterasu and the only way to defend himself against tobi is susanoo which he can obviously use longer than usual with EMS but eventually his chakra...
Itachi's fighting style, so far he's got the greatest balance about techniques, he's a master in genjutsu, ninjutsu and taijutsu, in 1v1 I highly doubt he would lose again someone