I wanted to say Dragon Ball, but at least it had characters like Bulma, Launch, and even Chichi. If we could split the anime seasons up, however, then Dragon Ball Z would be among the worst because they barely even exist. Legit just Android 18 and that's it, from all i remember.
EDIT: Oh, right, Videl. Forgot she was a thing. Goddamn, you're actually right.
Wait, all of the most prominent female characters in the series (Videl, Chichi, Bulma, Android 18), which the exception of Launch, start off as badasses but then just end up being just pregnant housewives in the end. Holy shit. I worry for Cheelai now.