As far as my Japanese language studies go, it does seem like it's a literal translation. Sennen=thousand years, but frankly we'd have to find more qualified translators. It would make sense that 1000 years ago there MIGHT be some big thing that motivated Genryuusai to finally say..."Kill the...
Re: 382 Predictions [Naruto]
For some reason, I'm thinking Pain may be the Hanzo guy still screwing around with the Sannin, it makes some sense in retrospect of Jiraiya making reference TO Hanzo at all in reference to Pain supposedly killing him...and there's always that theory of multiple...