I guess it kinda depends.... For one thing, within human levels the amount of nen is not what is important. Murao, hisoka, kuroro, other ryodan members, kaito.... as far as basic nen abilities are concerned it is very likely that they have very similar levels. Even if that were to not be the case it is very likely fights between them would in themselves be very close. Even bisk would likely be of the same level of people you just mentioned, she is 50 years old after all, she has had more than enough time to more than master nen (even if her ability has no battle applications so far).
---------- Post added at 02:27 PM ---------- Previous post was at 01:24 PM ----------
now that I think about it, there is an issue as far as comparing those who we know.... What is our measuring scale so far? For the most part gon and killua since they are pretty much the weakest guys around. Their nen level gets praised every now and then but it also gets immediately shut down. Based on what we have seen from gon and killua, is there a skill difference between bisk, murao, knuckle, hisoka and a number of other people they have fought? I would argue that no... Gon and killua are remarkably weak in the grand scheme of things, by all intents and purposes novices at best. Remember the knuckle fights? Gon fought knuckle a number of times. After each fight he got a bit stronger due to bisk's training as we saw. He increased his nen significantly to say the least as he went from maintaining his ren from little under an hour to easily over an hour. Of course for a reinforcement type like gon such an improvement is significant, and what was the result of it? Knuckle beat the crap out of gon with ease. Basically, as much as gon's strength has improved through the manga he still has not gotten to a point where he could be considered strong in the grand scheme of things. Seriously, isn't it kinda strange that knuckle, and gensuru at large did beat the crap out of gon with the same ease? Gon only won against gensuru because he prepared thoroughly for that fight in all honesty, other than that it was clear gon could not even land a punch.... Now, does this necessarly suggest that people like gensuru or knuckle would stand a chance against hisoka? Not really actually. What I am ultimately trying to say is that we have no idea of how much of a difference there is between people who have been shown to be capable of beating the crap out of gon and killua.
Another interesting point is that people at times have argued that the ryodan is not so strong because they had trouble against the ants. Does this make a lot of sense though? We actually saw a couple of ants give people like murao or knuckle a decent bit of trouble. This is significant as murao is easily one of the strongest nen users we have seen (to the point where he is still knuckles teacher). Based on this I would argue that gon and killua are lucky they did not run into ant captains or commanders as they would have been killed considering the trouble they gave the ryodan or murao....